Pharmacy: Diabetic Medications and Insulin Pump Therapies

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Learning objectives: 

  • Describe the normal processing of blood glucose in a healthyperson.
  • Discuss the altered processing of blood glucose in diabetic patients.
  • Recognize the effects of sulfonylureas on blood glucose control,cardiovascular effects of sulfonylureas, their adverse reactions, andthe currently available sulfonylureas.
  • Describe the characteristics of meglitinides, including effects onblood glucose control, cardiovascular effects, adverse reactions, andthe medications available in this class.
  • Discuss metformin’s effects on blood glucose control,cardiovascular effects, and its potential adverse reactions.
  • Recognize the characteristics of thiazolidinediones, includingeffects on blood glucose control, impact on cardiovascular health,and contraindications to the use of this class of medication.
  • Explain the effects of amylin analogs on blood glucose control,cardiovascular effects, adverse reactions, and their dosing.
  • Describe the characteristics of alpha glucosidase inhibitors,including effects on blood glucose control, cardiovascular effects,and the dosing and availability of these agents.
  • Discuss the characteristics of glucagon-like peptide-1 (GLP-1)receptor agonists, including effects on blood glucose control,cardiovascular effects, adverse reactions, and the use of short-acting vs. long-acting agents.
  • Explain the characteristics of dipeptidyl peptidase-4 (DPP-4)inhibitors, including effects on blood glucose control,cardiovascular effects, adverse reactions, and the currently availableDPP-4 inhibitors.
  • Identify the characteristics of sodium-glucose cotransporter 2(SGLT-2) inhibitors, including effects on blood glucose control,common adverse reactions, and the currently available SGLT-2 inhibitors.
  • Discuss the available insulin products, including the differencebetween basal and prandial insulin, the insulin products currentlyavailable, common types of insulin regimens, and the use of insulin pumps.

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