German Research Team Working to Allow Medicines to Release Sequentially

Key discovery for patients taking numerous medications

Scientists and pharmacists have long dreamed of a scenario in which they could prescribe and distribute different medications without fear of adverse interactions. Recent discoveries may move them ever closer to that goal.

Thanks to the work of a team at the Technical University of Munich (TUM), nanoparticles can be released in sequence under conditions similar to those in the human body.

It is becoming much more common for patients to be treated with several different medications. It is often necessary for the patient to take them at fixed intervals—a limitation that makes everyday life difficult and increases the risk of doses being skipped or forgotten.

Oliver Lieleg, a professor of biomechanics and a member of the Munich School of BioEngineering at TUM, and doctoral candidate Ceren Kimna have now developed a process that could serve as the basis for medications containing several active ingredients that would reliably release them in the body in a predefined sequence at specified times. 

“For example, an ointment applied to a surgical incision could release pain medication first, followed by an anti-inflammatory drug and then a drug to reduce swelling,” explains Oliver Lieleg.

SOURCE: World Pharma News

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